In 1997, a published study from the University of Hawaii found that Noni fruit appears to enhance the production of nitric oxide in the body. Anne Hirazumi, PhD., the main researcher on the project and considered by some to be the top Noni researcher, found “Noni effectively enhanced the production of nitric oxide."

Nitric oxide is not to be confused with nitrous oxide, or laughing gas. Instead, small amounts of nitric oxide have been shown to be beneficial in the body, aiding the immune and circulation systems. Noni extracts have been found to promote the biosynthesis of nitric oxide, giving the body the ability to lower blood pressure, fight cardiovascular disease, and slow down viral and bacterial activity.

The national magazine, "Science," chose nitric oxide as "Molecule of the Year" in 1992. The 1998 Nobel Prize for Medicine was awarded to three researchers for their discovery that nitric oxide acted as a signaling molecule in the cardiovascular system. They found nitric oxide is involved in controlling the circulation of blood and regulating activities of the brain, lungs, liver, kidneys, stomach and other organs.

In the cardiovascular function of the body, nitric oxide has been shown to relax and expand blood vessel walls. This makes them more elastic and results in lower blood pressure, alleviating undue stress in the arteries and the heart.

The immune system uses nitric oxide in fighting viral, bacterial and parasitic infections and tumors. Nitric oxide helps the immune system’s macrophages, which are the cells in the body that are activated during injury and illness. They seek out invading bacteria or cancer cells to destroy.

Hirazumi, A. Rursawa, E., Chou, S.C., and Hohama, Y. "Anticancer activity of Morinda citrifolia (Noni) on intraperitoneally implanted Lewis Lung Carcinoma in syngenic mice". Pro. West Pharmacology Society 37 (1994): 145-146

Wright, Pearce. Association of British Science Writers. "Nitric oxide: From menace to marvel of the decade." London England: May 1996.


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